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Heroin detox typically takes 5 to 10 days, with the most intense withdrawal symptoms peaking between 48 and 72 hours after the last use and subsiding gradually over the following week. At Hollywood Hills Recovery, heroin detox is medically supervised around the clock, with physician-managed medications to minimize discomfort and prevent complications.

How Long Does Heroin Withdrawal Last?
The duration of heroin withdrawal depends on how long and how heavily a person has used, whether fentanyl was present in the supply, and the individual's overall health. Most people experience acute withdrawal for 5 to 10 days, while post-acute symptoms such as fatigue and mood instability can persist for weeks.
- Onset: withdrawal symptoms typically begin 6 to 12 hours after the last use of short-acting heroin
- Peak: the most severe symptoms usually occur between 48 and 72 hours and include nausea, muscle cramps, and intense anxiety
- Resolution: acute physical symptoms generally resolve within 5 to 10 days for most clients in a medically supervised setting
What Are the Symptoms of Heroin Withdrawal?
Heroin withdrawal produces both physical and psychological symptoms that vary in severity based on the degree of physical dependence. Without medical supervision, their intensity is one of the most common reasons people relapse before completing detox.
- Physical symptoms: nausea, vomiting, diarrhea, profuse sweating, goosebumps, muscle aches, and uncontrollable leg movements
- Neurological symptoms: insomnia, restlessness, extreme sensitivity to pain, and involuntary muscle spasms throughout the withdrawal period
- Psychological symptoms: intense anxiety, depression, irritability, and overwhelming cravings for opioids throughout detox
- Vital sign changes: elevated heart rate, blood pressure, and temperature are common and require ongoing medical monitoring

What Medications Are Used During Heroin Detox?
Medication-assisted treatment is the standard of care for heroin detox and significantly reduces the severity of withdrawal symptoms and the risk of early relapse. A supervising physician determines the appropriate medication protocol based on each client's history and degree of dependence.
- Buprenorphine (Suboxone): a partial opioid agonist that reduces withdrawal symptoms and cravings without producing the euphoric effects of heroin
- Methadone: a full opioid agonist used in tapering protocols for clients with long-term or high-dose heroin dependence
- Clonidine: a non-opioid medication that reduces anxiety, sweating, and blood pressure fluctuations during the acute withdrawal phase
How Is Heroin Detox at Hollywood Hills Different From Standard Detox?
Heroin detox at Hollywood Hills Recovery is conducted in a private residential setting with 24-hour nursing oversight, a lower client-to-staff ratio than standard detox facilities, and immediate access to the clinical team guiding the full residential program that follows.
- Private accommodations during detox reduce environmental stress and allow for more individualized attention from the nursing staff
- A psychiatrist screens each client during detox to identify co-occurring mental health conditions for treatment in the residential program
- Clients transition directly from detox into the residential inpatient program, eliminating the gap between detox and clinical treatment
- Holistic supports such as mindfulness and massage are available during detox to reduce physical discomfort and anxiety
What Comes After Heroin Detox?
Detox alone does not produce lasting sobriety. Clients at Hollywood Hills Recovery transition directly from detox into the residential program, where the psychological and behavioral roots of addiction are addressed through individual therapy, group therapy, and specialized clinical work.
- Individual therapy begins within the first days of residential admission to address the trauma or mental health conditions underlying heroin use
- Evidence-based therapies including CBT, DBT, and EMDR build the coping skills needed to sustain sobriety after discharge
- Aftercare planning begins during residential treatment and includes referrals to outpatient programs, sober living, and ongoing support resources
Learn more about the full detox and treatment process through the medical detox program at Hollywood Hills Recovery. Clients managing opioid dependence can explore heroin addiction treatment options and the residential inpatient treatment program that follows detox. Additional resources are available through our addiction guidance blog.






